Crosslinking, Labeling and Protein Modification
Crosslinking, Labeling and Protein Modification
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Thermo Scientific™ TMTpro™ 16plex Label Reagent Set
The Thermo Scientific TMTpro 16plex Label Reagent Set enables multiplexing of up to 16 samples for multiplexed protein identification and quantitation using tandem mass spectrometry (MS/MS).
Workflow Step | Protein Labeling |
---|---|
Final Product Type | Peptide |
For Use With (Equipment) | Mass Spectrometer |
Label or Dye | Tandem Mass Tag™ (TMT) Labels |
Detection Method | Mass Spectrometry |
Product Line | TMT™ |
Thermo Scientific™ Mass Spectrometry Cleavable Crosslinkers
Improve sensitivity of mass spectrometry detection of crosslinked proteins with MS-cleavable DSSO and DSBU heterotrifunctional crosslinkers.
Content And Storage | Upon receipt store at 4°C protected from moisture. |
---|---|
Cleavable | By CID using MS |
Water Soluble | No |
Form | Powder |
Solubility | DMF, DMSO |
Quantity | 10 x 1 mg |
Labeling Method | Chemical Labeling |
Crosslinker Type | Homobifunctional |
Chemical Reactivity | Amine-Amine |
Cell Permeability | Yes |
Format | Standard, Single-use |
Product Type | Crosslinker |
Spacer | Medium (10 to 30 Å) |
Reactive Moiety | NHS Ester |
PEGylated | No |
Thermo Scientific™ Super Heavy TMT Label Reagent
Alternate form of TMT that contains twice the number of heavy of isotopes for labeling of peptides, and when used with TMT-labeled samples, enables 2D TMT multiplexing applications for targeted quantitation
Thermo Scientific™ TMTpro™ Zero Label Reagent
Thermo Scientific TMTpro Zero Label Reagent serves as a 'light' tag for MS-level peptide quantitation for method optimization or use with the TMTpro 16 plex Label Reagent Set.
Shipping Condition | Dry Ice |
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Workflow Step | Protein Labeling |
Final Product Type | Peptide |
For Use With (Equipment) | Mass Spectrometer |
Label or Dye | Tandem Mass Tag™ (TMT) Labels |
Starting Material | Peptides |
Detection Method | Mass Spectrometry |
Product Line | TMT™ |
Thermo Scientific™ TMTpro 18-plex, TMTpro-134C, and TMTpro-135N Label Reagents
TMTpro label reagents are the next generation of tandem mass tags, designed to increase the level of sample multiplexing without compromising on protein identification and quantitation.
Product Type | Isobaric Label Reagent Set |
---|---|
Detection Method | Mass Spectrometry |
Thermo Scientific™ TMTsixplex™ Isobaric Mass Tagging Kit
Amine-reactive Thermo Scientific TMT Isobaric Mass Tagging Kits and Reagents enable multiplex quantitation of proteins extracted from cells and tissues from up to 6 samples using tandem mass spectrometry.
Workflow Step | Protein Labeling |
---|---|
Final Product Type | Protein |
For Use With (Equipment) | Mass Spectrometer |
Label or Dye | Tandem Mass Tag™ (TMT) Labels |
Starting Material | Cell Lysate |
Detection Method | Mass Spectrometry |
Product Line | TMTsixplex™ |
Thermo Scientific™ TMTsixplex™ Isobaric Label Reagent Set
Amine-reactive Thermo Scientific TMT Isobaric Mass Tagging Kits and Reagents enable multiplex quantitation of proteins extracted from cells and tissues from up to 6 samples using tandem mass spectrometry.
Workflow Step | Protein Labeling |
---|---|
Final Product Type | Protein |
For Use With (Equipment) | Mass Spectrometer |
Label or Dye | Tandem Mass Tag™ (TMT) Labels |
Starting Material | Cell Lysate |
Detection Method | Mass Spectrometry |
Product Line | TMTsixplex™ |
Thermo Scientific™ Mass Spectrometry Compatible Crosslinkers
Improve mass spectrometry detection of crosslinked proteins and interactions with DSPP and TBDSPP heterotrifunctional crosslinkers.
Content And Storage | Upon receipt store at -20°C protected from moisture. |
---|---|
Format | Standard |
Cleavable | No |
Product Type | Crosslinker |
Form | Solid |
Reactive Moiety | NHS Ester |
Spacer Arm Length | 4.3 Å |
Quantity | 50 mg |
Labeling Method | Chemical Labeling |
Crosslinker Type | Homotrifunctional |
Chemical Reactivity | Amine-Amine |
Product Line | MS Reagents |
PEGylated | No |